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Centers of Biomedical Research Excellence (COBRE)
Alaska
http://www.alaska.edu/canhr/
The Center for Alaska Native Health Research (CANHR) was established through a five-year grant awarded by the National Institutes of Health, National Center for Research Resources to the University of Alaska Fairbanks. The purpose of CANHR is to investigate weight, nutrition, and health in Alaska Natives. CANHR approaches this thematic focus from a genetic, dietary, and cultural-behavioral perspective. The funding comes through a program for Centers of Biomedical Research Excellence (COBRE). This project has been and is being developed in partnership with the Yukon-Kuskokwim Health Corporation (YKHC). The Center has offices at the University of Alaska Fairbanks (UAF) and at the University of Alaska Anchorage (UAA).
Hawaii
http://www.hawaii.edu/pceidr/index.htm
The Pacific Center for Emerging Infectious Diseases Research is part of a larger vision to establish research excellence in tropical medicine and infectious diseases. The Center is one of five pillar programs within the Asia-Pacific Institute for Tropical Medicine and Infectious Diseases. The other four anchor or pillar programs include the Pacific Center for AIDS Research, which is comprised of the RCMI-supported Pathobiology of HIV-Associated Disorders activity and the Hawaii HIV Immunology and Vaccine Core, the Retrovirology Research Laboratory, the Hawaii AIDS Clinical Trials Unit (ACTU) and the Hawaii NeuroAIDS Specialized Neuroscience Research Program (SNRP); the Pacific Rim Biodefense Center; the Pacific Asia Center for Disease Ecology; and the Pacific Center for Vaccine and Gene Therapy Research. The Center will galvanize the University of Hawaii at Manoa's position as a center of excellence for research and training in infectious diseases and as a regional reference center for the diagnosis and control of new, emerging and re-emerging microbial threats.
Hawaii
http://lmp.biomed.hawaii.edu/
The Cardiovascular Research Center (CVRC) is an independent research group within the University of Hawaii (UH), dedicated to developing a better understanding of human cardiovascular diseases. Researchers at the Cardiovascular Research Center work closely with local patient groups to study diseases of the heart and vasculature prevalent among the native Hawaiian and Pacific Islander populations. Originally founded in 2001, the Cardiovascular Research Center (CVRC) has grown to include over 40 faculty members, research personnel, and students.

The Cardiovascular Research Center was recently identified as a Center for Biomedical Research Excellence by the National Institutes of Health. Most of CVRC's funding is received from the NIH and from various other governmental and private organizations. This funding allows our center to continue to bring together excellent researchers from around the world to conduct cutting-edge cardiovascular research at our location in the beautiful valley of Manoa in Honolulu, Hawaii.
Idaho
http://www.sci.uidaho.edu/biosci/CRePE/
The Center for Research on Processes in Evolution (CRePE) at the University of Idaho (UI) brings together scientists that have expertise in evolutionary biology, structural biology, molecular biology, ecology, computational biology, genetic programming, and statistics to investigate the relative importance of various mutagenic processes on the tempo and trajectory of adaptive evolution, to detect and understand the functional significance of patterns that emerge during the course of evolution, and to develop computational approaches that improve our ability to understand the evolutionary history of functional domains in proteins, structural genes, and entire genomes. The fundamental knowledge gained from these studies will be of broad significance to biomedical science and provide insights to the mechanisms and significance of genetic variation in populations and how adaptive evolution shapes the phenotypic characteristics of all living organisms.
Idaho
http://www.ag.uidaho.edu/cobre/
This COBRE grant funds University of Idaho research in microbial pathogenesis and food-borne illness. Included are six investigators in the Department of Microbiology, Molecular Biology & Biochemistry, Department of Animal Veterinary Science and the Boise VA Medical Center. They form the core of the UI Center of Biomedical Research Excellence to Study the Molecular and Cellular Basis of Host-Pathogen Interactions. The center will strengthen and diversify this core to establish Idaho as a premier institution with this focus.
Montana
Infectious diseases remain the leading cause of death worldwide and the third leading cause of death in the United States. In addition, purposeful release of highly infectious agents into the environment has become a significant source for concern in regard to homeland security. Many highly infectious diseases important to the health of man, livestock, and wildlife, are zoonotic. This COBRE will develop a Center for Immunotherapies to Zoonotic Diseases at Montana State University that will make significant scientific contributions to the knowledge of the pathogenesis of zoonotic diseases.
Montana
http://www.umt.edu/csfn/
The NIH Center for Structural and Functional Neuroscience was established at The University of Montana as a Center for Biomedical Research Excellence (COBRE) through the Institutional Development Award (IDeA) program of the National Center for Research Resources (NCRR). The research mission of the Center is to utilize approaches at the interface of chemistry, biochemistry, pharmacology, toxicology and molecular biology to advance our understanding of protein structure and function in the central nervous system, particularly as related to signal transduction, transport, development and pathogenesis.
Montana
http://www.umt.edu/cehs/
The Center is responsible for conducting research, teaching, and community service. The primary research mission of the Center is to advance knowledge of environmental impacts on human health.
Nevada
http://www.unr.edu/med/dept/pharmacology/COBRE/
Comprehensive research program to study the function and role of chloride channel transport proteins in cardiovascular disease.
Nevada
http://www.unr.edu/med/
The NIH Center was established at The University of Nevada, School of Medicine as a Center for Biomedical Research Excellence (COBRE) through the Institutional Development Award (IDeA) program of the National Center for Research Resources (NCRR).
New Mexico
http://hsc.unm.edu/som/cobre/
The Integrative Neuroimaging Center (INC) was established as a Center of Biomedical Research Excellence (COBRE) in February, 2001, with funding from the National Center for Research Resources (NCRR) of the National Institutes of Health (NIH). The Center creates a state-of-the-art research facility to promote advances in integrative multimodal neuroimaging research. The Center's research is currently focused on ischemic stroke, hemorrhagic stroke, traumatic brain injury and epilepsy. This facility is open to all scientists who are interested in using neuroimaging tools to discover the mechanisms of brain functions in both health and disease. We welcome foreign and domestic scientists to help us create an exciting international research enviroment.
New Mexico
http://biology.unm.edu/CETI/index.htm
The Center for Evolutionary and Theoretical Immunology (CETI) was developed to provide a nurturing and vibrant environment where young scholars with interests in theoretical and evolutionary immunobiology can prosper intellectually and ultimately become independently funded to pursue their research interests.
Wyoming
http://uwadmnweb.uwyo.edu/cardio%2Dcobre/
The scientific theme of this center is the study of the cellular responses to stressors that result in cardiovascular disease. Heart disease that kills more that half a million Americans each year. The Cardiovascular COBRE Program studies the genetic, cellular, and physiological factors that influence overall cardiovascular function in health and disease.
Wyoming
http://uwadmnweb.uwyo.edu/nocobre/
Biology of Spatiotemporal Nitric Oxide Gradients. This program contains 5 research projects with a central theme of elucidating the role of nitrous oxide (NO) concentrations and gradients as signals and as protective or damaging factors in the progression.